Youri Tielemans opened his Monaco account as last season's semi-finalists held RB Leipzig to a 1-1 draw to deny Ralph Hasenhuttl's side an historic victory on their Champions League bow.
The big-money signing from Anderlecht struck two minutes after Emil Forsberg scored his club's first goal in Europe's elite competition, with their first shot on target.
The 25-year-old timed his run to perfection to latch onto a ball down the left channel, before cutting into the penalty area and lashing the ball emphatically past Diego Benaglio with just over half an hour on the clock in this Group G encounter.
It was pure ecstasy for the newcomers, but their joy turned to sorrow only two minutes later when Monaco levelled, as Tielemans silenced the raucous home crowd when he capitalised on Peter Gulacsi’s fumble to tap in from close range.
Leipzig, founded in 2009, have enjoyed a rapid rise to the top of club football and, on this showing, Hasenhuttl's men proved they have the quality required to compete at this level.
The inexperienced hosts took their time to settle into the game initially and it was the visitors who created the first opportunity after seven minutes when Radamel Falcao's shot was blocked and Adama Diakhaby could not react quick enough to apply the finish.
Timo Werner has been Leipzig's standout player so far this season and he should have done better when Forsberg's corner delivery just evaded him at the back post.
The historic Leipzig goal finally came after 34 minutes, and in spectacular fashion. Forsberg was allowed to charge into the penalty area from the left channel before finishing emphatically past Benaglio.
But Monaco soon levelled as Tielemans silenced the raucous home crowd. Tielemans was at the back post to meet a superb right-wing cross, and though his first effort was blocked he was on hand to apply the finish from the rebound.
Leipzig ended the first half on a high and almost restored their lead when Lukas Klostermann's cross was inch-perfect for Werner, but Kamil Glik stepped in to make a crucial intervention.
The hosts started the second period on the front foot and when Werner - usually so prolific - broke into the box after 52 minutes, he was favourite to score. Agonisingly, he sent the ball inches wide of the post.
And just before the hour mark, Glik saved his goalkeeper's blushes when the Monaco defender cleared from the line after Benaglio had flapped at Forsberg's excellent corner delivery.
Leipzig's pressure was building and after 62 minutes, following a nice team move, Yussuf Poulsen had the ball in the back of the net, only for the goal to be ruled offside.
Benaglio had to be at his best to block Jean-Kevin Augustin's goal-bound effort in the latter stages as Leipzig had to settle for a point.
|Memorable Ashes Moments: Harmison sends down woeful opening wide as England´s defence wilts|
|Conte´s wife tells him to grow a beard – Conte grows a beard|
|Simeone rules out Everton job, promising ´a couple of years at least´ at Atletico|
|Pique to miss Barcelona´s Leganes trip over personal matter|
|Serena Williams reportedly marries Alexis Ohanian in New Orleans|
|UEFA closes Roma ´monkey chanting´ case|
|Swinson set to miss Six Nations after finger surgery|
|Don´t worry about Messi renewal, Valverde tells Barcelona fans|
|Cheika disrespected referee - Jones|
|´Griezmann? We´ll see´ – Valverde won´t rule out Barcelona pursuit of Atletico star|
|Cardinals & Larry Fitzgerald agree to 2018 contract extension|
|Uncapped Enever replaces injured Coleman for Twickenham clash|
|Goffin overcomes slow start & Thiem to set up Federer semi|
|Unsworth surprised to see Allardyce snub Everton|
|Six-week stadium ban for Sale boss Diamond|
|Mourinho has ´immense respect´ for Benitez|
|Howe backs Defoe to make World Cup squad|
|Everton speculation out of my control - Silva focusing on Hornets|
|Conte concerned by Manchester City´s breakaway lead|
|Man City results ´perfect´, but Guardiola demands improvement|
|David Luiz back in Chelsea squad, Conte confirms|
|Recovered Klopp offers Liverpool fitness update|
|Guardiola confident Aguero in ´perfect´ condition despite hospital trip|
|Ibrahimovic, Pogba and Rojo back for Manchester United|
|Fleetwood and Rose look set for desert duel, Fitzpatrick leads in Dubai|
|Heynckes compiling list of potential successors|
|Modric & Carvajal fit for Madrid derby|
|Bayern begin talks over Wagner deal|
|Pulis angered as Chadli sidelined for ´foreseeable future´|
|Neymar to join Ronaldo at Real Madrid? Zidane speaks out on PSG star|
|Edinburgh banking on Barclay after signing Scotland captain|
|Guardiola & Sane complete Man City award double|
|Five-try Holmes makes history as Kangaroos batter Samoa|
|Brave Chapecoense secure top-flight status|
|Mooney seals Australia Women´s Ashes victory|
|Tottenham have overtaken Arsenal as north London´s best - Sherwood|
|Brisbane Roar 3 Melbourne City 1: Papadopoulos at the double as hosts finally win|
|Seaman: Wenger must start Lacazette against Tottenham|
|I am more than just a goal machine - Ronaldo ignores Real Madrid criticism|
|Pujara shows resistance on another rain-affected day|
|Skriniar not interested in Barcelona speculation|
|France need Benzema, says Aulas|
|Warne: Australia look confused ahead of Ashes|
|Donald recovering after being hospitalised with chest pains|
|Youngs braced for ´confrontational and confident´ Wallabies|
|The Breakdown: A statistical look at Saturday´s rugby internationals|
|Van Dijk could leave Southampton in January|
|Sanchez snubbed Barcelona switch - Osorio|
|Malan posts century as England impress in Townsville|
|Atletico Madrid v Real Madrid: Simeone and Zidane face dangerous, defining Derbi|
|Aubameyang baffled by Dortmund suspension|
|Harden scores 48 points as Rockets soar|
|George, Hauritz and Tendulkar – Ashes surprise Paine´s last Test|
|He´s a class player - Hussey approves of Marsh recall for Ashes|
|Brown stars as Steelers crush Titans|
|Smith backs ´terrific´ Paine ahead of Ashes|
|Celtics claim 14th straight victory with comeback win over Warriors|
|WATCH: Brown makes incredible helmet catch for Steelers|
|´Surprised´ Paine thought Test career was over|
|Steelers QB Roethlisberger reaches new career milestones|
|Pochettino lauds Wenger longevity as he eyes 20 years at Spurs|
|Ronaldo: Real Madrid don´t fear PSG|
|Australia´s Paine pick an amazing Ashes gamble|
|Bancroft demanded Ashes spot, others were mediocre – Hohns|
|Zenit´s Mancini not thinking about Italy job|
|Altuve, Stanton named MVPs|
|Wenger advises Pochettino to fight the ´fear´ of winning trophies|
|Kirk leads RSM Classic after fine 63|
|Red Wings defenseman Witkowski handed 10-game ban after brawl|
|Broad backs Root to reach ´another level´ during Ashes|