Stoke City manager Mark Hughes has revealed his side could face Chelsea on Saturday with just one available central defender.
Ryan Shawcross (back) and Geoff Cameron (hamstring) are still injured, while Kurt Zouma is ineligible to play against his parent club.
Hughes also confirmed Kevin Wimmer is struggling for fitness after sustaining a hamstring injury during the 2-0 EFL Cup defeat to Bristol City on Tuesday.
That leaves Bruno Martins Indi as the only first-team centre-back for the visit of the defending Premier League champions to the bet365 Stadium.
"We're struggling a little bit defensively," he said.
"Of my senior centre-halves I've probably got one. We're keeping our fingers crossed Kevin will be okay. He's got damage to his hamstring and we're hoping it won't stop him playing, but clearly at the moment he's a big risk.
"Obviously if you have three or four injuries in the same position you haven't got depth. That's where we find ourselves and it's coincided with the fact we can't play Kurt. We're a little bit stretched, to say the least."
Hughes will be relieved his makeshift defence does not have to contend with Diego Costa, who arrived in Spain on Friday to complete his impending move to Atletico Madrid.
The Stoke boss lamented Costa's departure as "a real shame" and admits he will miss the striker's combative presence in the Premier League.
"I don't know the whole circumstances, but from a football fans' point of view I think he's a loss to the Premier League," said Hughes.
"I used to really enjoy watching him go about his business because he was different - he had an edge, and the reaction of other players to him was interesting.
"Whatever happened and why, maybe both sides should have got together and got a real positive out of it. As it is he's left Chelsea and the Premier League and that's a real shame."
|Dyche not aware of any approach amid Leicester speculation|
|I love you, take my watch! – How Arnautovic earned a special gift from Mourinho|
|Hafeez reported for suspect bowling action|
|´Surprised´ Appleton calls for Foxes focus after Shakespeare sacking|
|Harris: Stokes should follow Warner´s example|
|Brighton boss Hughton feels ´unacceptable´ behaviour remains in football|
|Markram replaces rested Amla for final ODI|
|Benzema ´very happy´ at Real Madrid amid Arsenal rumours|
|Azpilicueta admits to low mood in Chelsea camp|
|Lozowski ends exit talk by signing Saracens extension|
|Button reveals where he plans to race in 2018|
|Bacca: I played for the worst AC Milan in history|
|I don´t want the dog meat, I want the dog himself - Saunders targeting Golovkin or Canelo|
|Aluko ´100 per cent´ in England contention, says interim boss|
|Injured Napoli striker Milik hints at loan move|
|Dortmund not expecting Reus exit|
|Neymar plans to emulate Messi by mentoring Mbappe|
|Mourinho still unclear on fitness of Pogba and Fellaini|
|Wests Tigers centre Idris retires at 27|
|Sodhi replaces injured Astle in New Zealand´s ODI squad|
|Heynckes happy with Muller form|
|Kane describes Ronaldo as ´role model´ following shirt swap|
|PSG star Mbappe: Monaco need time|
|I have full support of Everton board, claims Koeman|
|England have the right balance for Ashes - Bairstow|
|Thomas pulls clear in South Korea|
|Timberwolves, 76ers fall in anticipated openers|
|Cubs stay alive, Yankees poised to reach World Series|
|Girardi calls Tanaka ´special´ after game five masterpiece|
|Cubs´ Maddon ejected after umpires reverse controversial call|
|Brown hails ´exceptional´ Simmons after 76ers debut|
|Wilshere: Arsenal´s character can´t be questioned|
|Simmons replaces Rodda as Hunt misses out for Wallabies|
|No-one can compete with Messi – Bartomeu|
|Brennan named Titans coach|
|Man United risk losing identity under Mourinho – Bellamy|
|Hayward delivers message to Celtics fans from hospital bed|
|Valverde hopes Messi scores 200th European goal this season|
|Storm, Cowboys to meet in round three in 2018|
|Dodgers´ Roberts all too familiar with historic 3-0 comebacks|
|Maddon on staving off elimination: Cubs have to start hitting ball|
|Stop worrying about Chelsea – Conte hits back at Mourinho|
|Roma better than Chelsea, says Nainggolan|
|Bemelmans stuns Kyrgios in Antwerp, Sock back on track in Stockholm|
|Basel coach Wicky demands more focus|
|Heynckes calls for patience from Bayern´s reserve stars|
|Emery calls for PSG improvement despite perfect start|
|Pique handball instinctive, says Barcelona boss Valverde|
|Dzeko was born to score – Di Francesco|
|Lemonis rues Olympiacos collapse against 10-man Barca|
|Rodgers: Individual class inhibiting Celtic|
|David Luiz experiment failed, admits Conte|
|Banvit claim first win as Petrol Olimpija run out of gas|
|Allegri not impressed despite crucial win|
|Svilar risks a lot – Mourinho was aware of Benfica youngster´s shortcomings|
|We played better against Atletico – Hazard|
|Job done for Mbappe and PSG after another big win|
|Colts QB Luck suffers setback in recovery from shoulder injury|
|Simeone maintains ´absolute´ belief in Atletico despite Qarabag draw|
|Mladenovic slump continues in Moscow, Kontaveit crashes out in Luxembourg|
|Louisville fires AD Tom Jurich amid pay-for-play scandal|
|CSKA Moscow 0 Basel 2: Xhaka, Oberlin do the damage|
|Juventus 2 Sporting CP 1: Late Mandzukic intervention saves wasteful Bianconeri|
|Bayern Munich 3 Celtic 0: Hoops outclassed on Heynckes´ return to Europe|
|Chelsea 3 Roma 3: Hazard brace rescues Conte´s men after Dzeko double|
|Anderlecht 0 Paris Saint-Germain 4: Mbappe takes one record as Cavani closes on another|
|Barcelona 3 Olympiacos 1:Ton-up for Messi as Pique sees red|
|Benfica 0 Manchester United 1: Rashford goal settles poor game after woeful Svilar error|
|Sopoaga replaces injured Barrett for Bledisloe clash|
|Messi joins Ronaldo in European 100-goal club|